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Text File  |  1987-10-07  |  525b  |  15 lines
  1.  
  2.          IN PATIENTS WITH RENAL IMPAIRMENT, METHICILLIN DOSAGE SHOULD
  3.          BE CAREFULLY ADJUSTED TO AVOID TOXICITY (ALLERGIC
  4.          INTERSTITIAL NEPHRITIS, SEIZURES, AND COAGULOPATHY).
  5.           
  6.          SOME CLINICIANS RECOMMEND THAT THE DOSAGE REGIMEN BE
  7.          ADJUSTED BASED ON THE PATIENT'S CREATININE CLEARANCE:
  8.           
  9.                 CREATININE
  10.                  CLEARANCE           DOSAGE
  11.                 (ML/MINUTE)
  12.           
  13.                    <10          1g Q 8 to 12 hours
  14.           
  15.